Rana Chakraborty, MD, MSc, FRCPCH, DPhil
Emory Vaccine Center
Department of Pediatrics, Division of Infectious Diseases
Ponce Family and Youth Clinic
Emory Center for AIDS Research
Committee on Pediatric AIDS, American Academy of Pediatrics
Prevention of MTCT of HIV-1 provides an excellent model to identify correlates of protection from infection. We are examining placental antigen presenting cells in HIV-1-exposed and unexposed newborns. The ability of HIV-1 to replicate in these cells will be assessed in a tissue culture model and innate antiviral molecules that limit replication will be defined.