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HIV/AIDS Research at the Emory Vaccine Center

hiv research

Developing a vaccine to halt the AIDS epidemic is a key part of the mission of the Emory Vaccine Center, and a significant portion of the research at the EVC relates to this effort. Several aspects of the biology of the Human Immunodeficiency Virus (HIV) and the pathogenesis of its infection make the design of candidate AIDS vaccines a tremendously complex challenge, that can be approached only with a comprehensive strategy that includes basic science approaches, translational animal studies, and, ultimately, clinical trials in humans.
The Emory Vaccine Center has been at the forefront of this challenge for over a decade, thanks to the pioneering work of Drs. Harriet Robinson, Eric Hunter, Rafi Ahmed, Guido Silvestri, Rama Amara, and others, and continues to be at the center of major NIH initiatives in this field, including the recently awarded "Consortia for AIDS Vaccine Research in Nonhuman Primates". Scientists specializing in basic immunology strive to elucidate the fundamental mechanisms by which the immune system responds to HIV infection.
Other investigators examine the interaction between HIV and the host immune system in order to identify ways to prevent or interrupt the process by which the virus induces immunodeficiency. Finally, other researchers translate these findings into new AIDS vaccine strategies, which are tested rigorously in preclinical studies in non-human primates for safety and efficacy before being considered for human clinical trials.
The Hope Clinic of the Emory Vaccine Center, a freestanding clinic located in Decatur, Georgia, conducts vaccine clinical trials and related research studies involving human volunteers. Thus, the EVC’s AIDS vaccine program spans the entire research process, from basic science to translational research to preclinical and clinical trials.

Learn more about the Emory Vaccine Center HIV/AIDS Researchers:

Rafi Ahmed, PhD

Rama Rao Amara, PhD

Rana Chakraborty, MD, MSc, FRCPCH, DPhill

Richard Compans, PhD

Carlos del Rio, MD

Cynthia Derdeyn, PhD

Srilatha Edupuganti, MD, MPH

Eric Hunter, PhD

Christian Ibegbu, PhD

Paul Johnson, MD

Vincent Marconi, MD

Mark Mulligan, MD

Mirko Paiardini, PhD

Harriet Robinson, PhD

Nadine Rouphael, MD

Guido Silvestri, PhD

Jens Wrammert, PhD

Emory Vaccine Center HIV/AIDS Research in the News:

AIDS Vaccine 200 Mile Bike Ride Raises Hope for the Future of Vaccine Research

HIV Prevention Trials Ongoing

15th Annual AIDS Vaccine Bike Ride

HIV Vaccine Design Should Adapt as Virus Mutates

Navigating a Complex Maze: What we don't know about HIV may lead us to the right path for finding a vaccine

Moving the HIV Vaccine Forward