January 13, 2014 marks three years since the last case of polio in India, with official eradication certification expected in late March. Long considered the hardest place on earth to end polio, India is now a case study for how to mount a successful disease response effort under the most complex circumstances. India’s triumph over polio is a significant public health achievement, leaving a lasting impact on children's health in India and around the world. We have a unique window of opportunity to change history and end polio. We must capitalize on India’s achievement to end polio globally and protect the health of children everywhere for generations to come.