Steven E. Bosinger, PhD
Professor, Emory Vaccine Center
Associate Professor, Emory School of Medicine Department of Pathology and Laboratory Medicine
Scientific Director, Emory Nonhuman Primate (NHP) Genomics Core
Associate Director, Center for AIDS Research (CFAR) Systems Immunology Core
Steven Bosinger, PhD, is a researcher within the Emory National Primate Research Center's Division of Microbiology & Immunology and an Associate Professor in the Emory School of Medicine Department of Pathology & Lab Medicine. He obtained his PhD from the University of Western Ontario, and completed his postdoctoral training at the University of Pennsylvania.
Our laboratory is interested in understanding how significant viral pathogens like HIV-1 and SARS-CoV-2 cause disease, and in testing novel vaccines and treatments. For several years, we have studied how natural host species monkeys, such as the sooty mangabey, are able to remain disease free when infected with simian immunodeficiency virus. We are also interested in how the genetics of the antibody system (immunoglobulins) dictate vaccine efficacy. We use the nonhuman primate model, and advanced immunological genomic and bioinformatic tools to address these questions.
Research Interests:
Dr. Bosinger’s research program studies:
· the role of interferon in HIV infection and how it can be manipulated to reduce inflammation and enable HIV curative strategies.
· Nonhuman primate genomics for HIV/SIV studies – these include the recent sequencing of the sooty mangabey genome and building a reference of transcriptomes of immune cell subsets in NHP models of AIDS.
· Development of genomic tools and bioinformatics for the study of the immune system and vaccines in humans and primates, particularly using single cell RNA-Seq, antibody repertoire analysis.
Dr. Bosinger’s publications can be found here:
https://pubmed.ncbi.nlm.nih.gov/?term=bosinger+s&sort=date
https://scholar.google.com/citations?user=uXWsfoIAAAAJ&hl=en&oi=ao